Regenerative Wound Dressings Developed by Lithuanian Scientists Will Heal Deep Wounds

2018-04-12 12:30

Group of researchers at Kaunas University of Technology, Lithuania are developing new generation sponge-like wound dressings with hyaluronic acid. Antimicrobial, antioxidant, anti-inflammatory wound dressings stimulate tissue regeneration and can be especially efficient in treating deep wounds that are difficult to heal.

New generation sponge-like regenerative wound dressings created at KTU

According to data, of the total healthcare expenditure in the European Union, wound management makes up 2–4%. A single chronic wound can cost up to 10 thousand EUR to treat, and it is estimated that up to 1.5% of EU population has one or more of such wounds.

For deep wound to heal successfully, tissue regeneration is extremely important. Development of new generation wound dressings, which assist this process, is one of biggest challenges in tissue engineering. Kaunas University of Technology (KTU) researchers are developing sponge-like wound dressings based on hyaluronic acid, which is a well-researched polymer stimulating tissue regeneration and used in ophthalmology, bone regeneration and for other medical and cosmetic purposes.

“Hyaluronic acid is a natural polymer found in living organisms, which has anti-inflammatory properties and stimulates tissue regeneration. We are used to commercial hyaluronic acid based products, which usually are thick liquids or gels. Although quickly absorbed by the organism, in this form the polymer doesn’t have the structure needed for tissue building”, says Odeta Baniukaitienė, researcher at KTU Faculty of Chemical Technology.

Sponge-like wound dressings created at KTU have net structure, which is essential in developing wound dressings for tissue regeneration. Although biopolymers are often chosen for this purpose as they are compatible with biological systems, sponge-like wound dressings are mostly being made from alginate or collagen.

“We use freeze-drying technique to render hyaluronic acid sponge-like structure. The dressing fills in the wound, and is serving as a structure for cells to stick on; the active compounds, which have antimicrobial, antioxidant, anti-inflammatory or tissue regeneration stimulating qualities are in such a way fixed and carried through”, says Baniukaitienė.

At the moment, KTU researchers have built hyaluronic acid scaffolds, which can be used for tissue regeneration. Collaborating with the Lithuanian University of Health Sciences, the scientists are testing the prototype in vitro with different cells. According to researchers, the proof of concept stage research can take up a few more years.

  • New generation sponge-like wound dressings with hyaluronic acid
  • New generation sponge-like wound dressings with hyaluronic acid
  • Odeta Baniukaitienė, researcher at KTU Department of Polymer Chemistry and Technology
  • New generation sponge-like wound dressings with hyaluronic acid
     
  • New generation sponge-like wound dressings with hyaluronic acid
     
  • Odeta Baniukaitienė, researcher at KTU Department of Polymer Chemistry and Technology
     

Related news

2015-09-11 14:15
If You need an answer to the question „Why focus on Career?“ there is one given below. Katie Jarvis in her presentation will share some simple tactics and techniques that can help to focus and build Your career. Traditionally ‘Career development’ meant upward promotion. However, organisations are flatter and leaner...
2018-04-19 14:00
Kaunas 2022 Contemporary Capital together with Kaunas University of Technology (KTU) Faculty of Civil Engineering and Architecture and other partners is organising an International Summer School for students of architecture and heritage protection and professionals of these fields. The school is part of a wider series...
2018-04-19 14:00
Kaunas 2022 Contemporary Capital together with Kaunas University of Technology (KTU) Faculty of Civil Engineering and Architecture and other partners is organising an International Summer School for students of architecture and heritage protection and professionals of these fields. The school is part of a wider series...
2018-04-18 17:00
Team of researchers at Kaunas University of Technology (KTU), Lithuania are designing an innovative device, which will increase aircraft safety during takeoff. During the first 10 seconds of the takeoff roll, the device predicts if the aircraft will reach the sufficient speed for taking off. The idea behind the...
2018-04-18 16:00
On April 18–30 Kaunas will become the jazz capital of Lithuania. More than 20 free concerts in new and traditional spaces are only a small part of the programme, which features such internationally acclaimed artists as Laura Mvula and Gregory Porter. You will find the full programme of the events on Kaunas Jazz...
2018-04-17 11:15
Mechanical Engineering, Information Systems and Software Systems were the three Kaunas University of Technology (KTU) study programmes awarded the special Investor’s Spotlight quality label this year. The Label indicates that these programmes are matching the expectations of business and that their graduates are most...
2018-04-12 13:00
The demand for experts in aviation engineering is growing rapidly. “Given the trends and the speed as well as the extent to which aircraft depend on electronics, it is evident that there will be continued demand for avionics professionals,” says Karolis Čepukas, Kaunas Aircraft Maintenance (KAM) director in the...
2018-04-10 14:45
Kaunas University of Technology (KTU), Lithuania has been granted the right to coordinate European Institute of Innovation & Technology (EIT) Food Hub, which will promote innovations and entrepreneurship in the food science field. EIT Food Hub together with SMART Food cluster, uniting Lithuanian food industry...